Healthcare VC
Healthcare VC
Palo Alto, CA – November 3, 2025
Summary of the announcement regarding Hippocratic AI's Series C funding:
Hippocratic AI, a leader in safety-focused generative AI healthcare agents, has successfully closed its Series C financing round, raising $126 million.
Valuation: The funding was secured at a $3.5 billion valuation.
Total Funding: This brings the company's total funding to $404 million.
Lead Investor: The round was led by Avenir Growth.
Key Participants: Other major investors include new and existing participants like CapitalG (Google's growth fund), General Catalyst, Andreessen Horowitz (a16z), Kleiner Perkins, and prominent health systems such as Universal Health Services (UHS), Cincinnati Children's Hospital Medical Center, and WellSpan Health.
The announcement highlights significant company growth and its future strategy:
Rapid Growth: In just 15 months since commercialization, Hippocratic AI has partnered with over 50 large health systems, payors, and pharma clients in 6 countries.
Impact: The agents have executed over 1000 clinical use cases and completed over 115 million clinical patient interactions with no safety issues.
Focus on Safety: The company's core mission is a "do no harm" philosophy, with their agents focusing on low-risk, non-diagnostic, patient-facing tasks to help address the healthcare labor shortage.
Funding Use: The capital will be used to accelerate product development, expand customer deployments worldwide, invest in its proprietary Polaris Safety Constellation Architecture, and pursue strategic mergers and acquisitions.
“Every call our agents make is a patient whose life we have helped to make healthier. What this capital allows us to do is touch more lives and help more people while staying true to our core values of “do no harm” and “patients first”. “We truly believe that Generative AI agents can help bring in an era of abundance to healthcare never seen before." - Munjal Shah, Co-founder and CEO of Hippocratic AI
“At Avenir, we focus on investing in category leaders. After speaking with a significant number of customers prior to investing, we believe Hippocratic AI is leading the agentic healthcare category. Importantly, we found that their relentless focus on safety has earned them the trust of healthcare organizations around the world, becoming the safe choice for executives when choosing AI agents for deployment in healthcare.” - Andrew Sugrue, Co-founder of Avenir Growth
“Hippocratic AI is amongst the fastest growing enterprise healthcare companies we’ve seen in the last few years. Their rapid growth is a testament to the demand for solutions to our industry’s labor and patient access crisis, and the unique capabilities that Hippocratic has brought to market to address those needs.” - Julie Yoo, General Partner at Andreessen Horowitz
“At General Catalyst, our Health Assurance vision centers on enabling a system of care that is more proactive, affordable, and accessible care. We believed in Hippocratic AI and the team since inception, and it is a shining example of this thesis in action. They are applying clinically safe, empathetic generative AI in ways that expand access and dignity in care. Their rapid success reflects both their breakthrough solution and the moral imperative to reimagine how care is delivered.” - Hemant Taneja, CEO of General Catalyst
“Hippocratic AI’s focus on safety, empathy, and clinical alignment makes them a trusted partner as we explore new ways to engage and support our patients and members at scale". - David Newman MD, Chief Medical Officer of Virtual Care at Sanford Health
“Hippocratic AI’s focus on safety and scale mirrors our mission to support the care team in providing the highest quality pediatric care to every child who needs it. “The AI agents open up new opportunities to support families with warmth and precision, whether in scheduling, chronic condition management, or daily guidance.” - Oliver Rhine, Chief Strategy Officer and President of Cincinnati Children’s Global
“At OhioHealth, safety is the cornerstone of every care decision we make, and we hold our partners to the same standard. “Hippocratic AI’s unwavering commitment to clinical safety, combined with their rigorous testing and validation process, gives us the confidence to deploy their agents in ways that truly support patients and clinicians alike.” - Dr. Michael Ezzie, MD, the Senior Vice President and President of OhioHealth Physician Group
“The safety information on Anna (the name WellSpan Health gave its Hippocratic AI agent) as our AI care assistant is absolutely terrific. We monitor that all the time along with your team. And every one of our clinical leaders and chief medical officers who’ve reviewed that has been very impressed". - Roxanna Gapstur, PhD, RN, President and Chief Executive Officer of WellSpan Health
“We see AI as a powerful tool to expand our ability to serve patients without expanding clinician burden. What sets Hippocratic AI apart is its uncompromising commitment to empathy, reliability, and clinical safety.” - Dr. Paul R. Hinchey, MD, MBA, Chief Operating Officer of University Hospitals
“At Advocate Health, we are committed to using AI in partnerships that amplify and enhance human connection rather than replace it. Guided by our robust responsible AI framework, we’re leveraging AI agents to make patient conversations more accessible, empathetic and clinically safe while reducing the administrative burden on our care teams. We value partners that focus on real-world safety and co-development of products, helping us deliver timely, personalized communication that builds trust and supports better patient outcomes,” - Andy Crowder, Chief Digital Officer at Advocate Health
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